Wrongly imprisoned on a murder charge, John Brant (John Wayne) escapes from his cell and joins a bunch of desperadoes in an attempt to find the true murderer.
When Randy is jailed for murders that he did not commit, Sally Rogers breaks him out of jail, knowing he is innocent. On the run, he stumbles across the real murderer’s hideout.
During the American Civil War, Col. Cord McNally has left Lt. Ned Forsythe, in charge of a Union army payroll train. However, Confederates led by Capt. Cordona, hijack the train.